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Registered Standard Poodles with JRD (juvenile renal disease)/Renal Dysplasia
mode of inheritance: Dominant with incomplete penetrance
JRD (juvenile renal disease)/Renal Dysplasia
Juvenile renal disease (JRD), also known as renal dysplasia, is a recessive disease in standard poodles.
Both parent have to carry the gene(s) for the disease to appear in a puppy. The parents do not have to have
the disease themselves. In JRD, the development of the kidneys in utero is abnormal, and the kidneys remain
abnormal after birth, with fetal or immature cells in place of many normal kidney structures. Puppies can be
affected to different degrees, and sometimes only one pup in a litter will be affected, while all pups in another
litter may be affected. Most puppies with JRD are diagnosed before two years of age, and die before they are three.
Some puppies, however, have less affected kidney tissue or have only one kidney affected, and these puppies,
particularly if they are diagnosed before they are symptomatic, may live good quality lives for many years, with an
appropriate renal diet, water soluble vitamins and omega-3 fatty acid supplements. Although the renal damage is not
reversible, the quality and length of the puppy's life will certainly be improved by early treatment.
Registered Standard Poodles:
 George-JRD/standard poodle # 1 (Turbo Timothy Hibernia x Peppertree Lucy Lucille)
Majestic Cuchsy's Fiery Lass (Michael's Red Man Riggs x Majestic Red On The Sunnyside)
Good Win Against All Odds-JRD/standard poodle # 2 (Ch. Kaylen's Reason To Believe x Ch. Good Win One Tuff Cookie)
JJ litter (Graphic X Marmaloo)-JRD/standard poodle # 3 - 3 puppies in litter (Am/Fin/DK/Int Ch. Graphic Double Take x Fin Ch. Marmaloo My Fair Lady)
Amandier Lily Willow-JRD/standard poodle # 4 (Ch. Aftermath It's About Time x Amandier Promises Promises)
Parrish Hill Cassandra-JRD/standard poodle # 5 (Ch. Maestoso's Comic Relief X Ch. Pinafore Parrish Hill)
Graphic VII-JRD/standard poodle # 6 (Ch. King's Champagne Taste x Ch. Graphic Silverdollar)
Koa / Never registered (Ch Hanovia Chase's Highlander x Ch Chase's Incantation)
Lapponia's Nieidamanna (Am/Swed/Fin/Dan Ch Canmoy's Rubiazo x Swed/Fin/Dan Ch Lapponia's Samenieida)
Tyldesley Swirling Mist (Tyldesley Bluewater Splash x Neiger Misty Grey)
Admirations Sara Bella (Ch Kingsdown Candid Cameron x Thetans Admiration Natalie)
Diamonds Passionate Kisses (Kerry's Sir Romeo's Mocha x Fancy Diamond Lace Ecole)
Scarlett Rose (Belcanto Lords of Gondor My Brothers x Belcanto Jete Entrelace)
Links for Additional Information on JRD in standard poodles:
Dogenes Inc. a company dedicated to discovery of mutations that cause genetic diseases in dogs, and management and elimination of these diseases.
Juvenile Renal Disease (JRD) in Standard Poodles.
Clinical article on Juvenile Renal Disease (JRD) in Standard Poodles.
Kidney Disease in Dogs website: symptoms, diagnosis, treatment, management (medical and dietary), recipes, breed specific renal diseases, genetics, current research, bibliography and abstracts
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